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WB, IP

H, R, M

68KD

IgG1

PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. Store at -20°C. Do not aliquot the antibody.

WB: 1:2,000-5,000 IP:1:200

The Lamin B1 antibody can detects endogenous Lamin B1 protein.

ADLD, LMB1,LMNB1, MGC111419, OTTHUMP00000159218

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family 

of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled 

as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and 

gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1.